Secure antiretroviral therapy delivery in a resource-limited setting: streamlined to minimize drug resistance and expense
نویسندگان
چکیده
منابع مشابه
Survival of Extremely Preterm Neonates in a Resource-limited Setting
Background: Preterm birth is a major contributor to neonatal and under-five mortality, and births at lower gestational ages (GA) contribute more to these statistics. Most developed countries have succeeded in improving survival at extremes of GA, while most developing countries like Nigeria still lag behind. The objective of this retrospective study was to document the...
متن کاملEmergence of HIV drug resistance during first- and second-line antiretroviral therapy in resource-limited settings.
INTRODUCTION Antiretroviral therapy (ART) in resource-limited settings has expanded in the last decade, reaching >8 million individuals and reducing AIDS mortality and morbidity. Continued success of ART programs will require understanding the emergence of HIV drug resistance patterns among individuals in whom treatment has failed and managing ART from both an individual and public health persp...
متن کاملFirst-line antiretroviral therapy with nevirapine versus lopinavir-ritonavir based regimens in a resource-limited setting
OBJECTIVE To compare WHO first-line antiretroviral therapy (ART) with nonnucleoside reverse transcriptase inhibitors (NNRTI)-based regimen with a boosted protease inhibitor (bPI) regimen in a resource-limited setting regarding treatment outcome and emergence of drug resistance mutations (DRMs). METHODS Treatment-naive adults were randomized to nevirapine (NVP) or ritonavir-boosted lopinavir (...
متن کاملHepatotoxicity from first line antiretroviral therapy: an experience from a resource limited setting.
BACKGROUND Highly active antiretroviral therapy (HAART) has been associated with liver toxicity. The role of monitoring for liver toxicity has not been well studied in resource-limited settings (RLS). OBJECTIVES To determine the background prevalence and incidence of liver injury and describe the associated signs and symptoms of acute hepatitis after initiating HAART; and to determine the rol...
متن کاملTransmitted antiretroviral drug resistance in a low HIV prevalence setting
ii To my family and loved ones iii ACKNOWLEDGMENTS I would like to thank my project mentor Dr. Jeffrey Meier and my thesis supervisor and academic advisor, Dr. Tara Smith as well as the dedicated members of my thesis committee. I owe a debt of gratitude to the staff of the Department of Epidemiology, especially, Amy Sayer, whose guidance has been invaluable and integral to my academic career. i...
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ژورنال
عنوان ژورنال: HIV Medicine
سال: 2008
ISSN: 1464-2662,1468-1293
DOI: 10.1111/j.1468-1293.2008.00611.x